Structural mechanisms of acute VEGF effect on microvessel permeability.

@article{Fu2003StructuralMO,
  title={Structural mechanisms of acute VEGF effect on microvessel permeability.},
  author={Bingmei M. Fu and Shang Shen},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2003},
  volume={284 6},
  pages={H2124-35}
}
To investigate the ultrastructural mechanisms of acute microvessel hyperpermeability by vascular endothelial growth factor (VEGF), we combined a mathematical model (J Biomech Eng 116: 502-513, 1994) with experimental data of the effect of VEGF on microvessel hydraulic conductivity (L(p)) and permeability of various-sized solutes. We examined the effect of VEGF on microvessel permeability to a small solute (sodium fluorescein, Stokes radius 0.45 nm), an intermediate solute (alpha-lactalbumin… CONTINUE READING
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