Structural investigation into physiological DNA phosphorothioate modification

Abstract

DNA phosphorothioate (PT) modification, with sulfur replacing a nonbridging phosphate oxygen in a sequence and stereo specific manner, is a novel physiological variation in bacteria. But what effects on DNA properties PT modification has is still unclear. To address this, we prepared three double-stranded (ds) DNA decamers, d(CG(PX)GCCGCCGA) with its… (More)
DOI: 10.1038/srep25737

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@inproceedings{Lan2016StructuralII, title={Structural investigation into physiological DNA phosphorothioate modification}, author={Wenxian Lan and Zhongpei Hu and Jie Shen and Chunxi Wang and Feng Jiang and Huili Liu and Dewu Long and Maili Liu and Chunyang Cao}, booktitle={Scientific reports}, year={2016} }