Structural insights into recognition of triple-helical beta-glucans by an insect fungal receptor.

Abstract

The innate ability to detect pathogens is achieved by pattern recognition receptors, which recognize non-self-components such as β1,3-glucan. β1,3-Glucans form a triple-helical structure stabilized by interchain hydrogen bonds. β1,3-Glucan recognition protein (βGRP)/gram-negative bacteria-binding protein 3 (GNBP3), one of the pattern recognition receptors… (More)
DOI: 10.1074/jbc.M111.256701

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