Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid.

@article{Messing2010StructuralII,
  title={Structural insights into maize viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid.},
  author={Simon A J Messing and Sandra B Gabelli and Ignacia Echeverria and Jonathan T Vogel and Jiahn Chou Guan and Bao-Cai Tan and Harry J. Klee and Donald R McCarty and L. Mario Amzel},
  journal={The Plant cell},
  year={2010},
  volume={22 9},
  pages={2970-80}
}
The key regulatory step in the biosynthesis of abscisic acid (ABA), a hormone central to the regulation of several important processes in plants, is the oxidative cleavage of the 11,12 double bond of a 9-cis-epoxycarotenoid. The enzyme viviparous14 (VP14) performs this cleavage in maize (Zea mays), making it a target for the rational design of novel chemical agents and genetic modifications that improve plant behavior through the modulation of ABA levels. The structure of VP14, determined to 3… CONTINUE READING

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