Structural insights into cofactor recognition of yeast mitochondria 3-oxoacyl-ACP reductase OAR1.

@article{Zhang2013StructuralII,
  title={Structural insights into cofactor recognition of yeast mitochondria 3-oxoacyl-ACP reductase OAR1.},
  author={Yujie Zhang and Fangkun Ning and Xin Li and Maikun Teng},
  journal={IUBMB life},
  year={2013},
  volume={65 2},
  pages={154-62}
}
3-Oxoacyl-(acyl-carrier-protein) reductase (OAR1 or FabG, EC.1.1.1.100) is responsible for the first reductive step in fatty acid biosynthesis using Nicotinamide Adenine Dinucleotide Phosphate (NADPH) as a cofactor. Recent studies suggest there is a fatty acid synthetase II pathway that consists of a series of separate enzymes in yeast mitochondrion. Here… CONTINUE READING