Structural insights into antibody-mediated mucosal immunity.

  title={Structural insights into antibody-mediated mucosal immunity.},
  author={Agnes E Hamburger and Pamela J. Bjorkman and Andrew B Herr},
  journal={Current topics in microbiology and immunology},
The mucosal regions of the body are responsible for defense against environmental pathogens. Particularly in the lumen of the gut, antibody-mediated immune responses are critical for preventing invasion by pathogens. In this chapter, we review structural studies that have illuminated various aspects of mucosal immunity. Crystal structures of IgA1-Fc and IgA… CONTINUE READING