Structural insights into ABC transporter mechanism.

Abstract

ATP-binding cassette (ABC) transporters utilize the energy from ATP hydrolysis to transport substances across the membrane. In recent years, crystal structures of several ABC transporters have become available. These structures show that both importers and exporters oscillate between two conformations: an inward-facing conformation with the substrate… (More)
DOI: 10.1016/j.sbi.2008.09.007

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Cite this paper

@article{Oldham2008StructuralII, title={Structural insights into ABC transporter mechanism.}, author={Michael L. Oldham and Amy L. Davidson and Jue Chen}, journal={Current opinion in structural biology}, year={2008}, volume={18 6}, pages={726-33} }