Structural insight into function and regulation of carnitine palmitoyltransferase

Abstract

The control of fatty acid translocation across the mitochondrial membrane is mediated by the carnitine palmitoyltransferase (CPT) system. Modulation of its functionality has simultaneous effects on fatty acid and glucose metabolism. This encourages use of the CPT system as drug target for reduction of gluconeogenesis and restoration of lipid homeostasis… (More)
DOI: 10.1007/s00018-009-0035-1

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@article{Rufer2009StructuralII, title={Structural insight into function and regulation of carnitine palmitoyltransferase}, author={Arne Christian Rufer and Ralf Thoma and M. Hennig}, journal={Cellular and Molecular Life Sciences}, year={2009}, volume={66}, pages={2489-2501} }