• DOI:10.1007/s00018-006-6252-y
Corpus ID: 13432321

Structural genomics for membrane proteins

@article{Lundstrom2006StructuralGF,
  title={Structural genomics for membrane proteins},
  author={K. Lundstrom},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2006},
  volume={63},
  pages={2597-2607}
}

• K. Lundstrom
• Published 2006
• Biology, Medicine
• Cellular and Molecular Life Sciences CMLS

Abstract.Structure-based drug discovery has proven useful in improving and shortening the drug development process. The approach of structural genomics to study a large number of targets in parallel has been commonly applied to protein families and even whole genomes. Paradoxically, although membrane proteins represent the largest type of drug targets, up to 70% today, determination of their structure has been modest compared to that of soluble proteins. Because membrane proteins are important… Expand

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