Structural features of heterotrimeric G-protein-coupled receptors and their modulatory proteins

Abstract

Over the past 20 years, the general mechanism for signaling through 7-transmembrane helix receptors coupled to GTP hydrolysis has been worked out. Although similar in overall organization, subtype variability and subcellular localization of components have built in considerable signaling specificity. Atomic resolution structures for many of the components… (More)
DOI: 10.1007/BF02743657

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Cite this paper

@article{Levine1999StructuralFO, title={Structural features of heterotrimeric G-protein-coupled receptors and their modulatory proteins}, author={Harry Levine}, journal={Molecular Neurobiology}, year={1999}, volume={19}, pages={111-149} }