Structural effects of the dispersing agent polysorbate 80 on liquid crystalline nanoparticles of soy phosphatidylcholine and glycerol dioleate.

@article{Wadster2015StructuralEO,
  title={Structural effects of the dispersing agent polysorbate 80 on liquid crystalline nanoparticles of soy phosphatidylcholine and glycerol dioleate.},
  author={Maria Wads{\"a}ter and Justas Barauskas and Sarah F Rogers and Maximilian W. A. Skoda and Robert K Thomas and Fredrik Tiberg and Tommy Nylander},
  journal={Soft matter},
  year={2015},
  volume={11 6},
  pages={1140-50}
}
Well-defined, stable and highly structured I2 (Fd3̅m) liquid crystalline nanoparticles (LCNP) of 50/50 (wt/wt) soy phosphatidylcholine (SPC)/glycerol dioleate (GDO), can be formed by using a low fraction (5-10 wt%) of the dispersing polymeric surfactant polyoxyethylene (20) sorbitan monooleate (polysorbate 80 or P80). In the present study we used small angle neutron scattering (SANS) and deuterated P80 (d-P80) to determine the location and concentration of P80 within the LCNP and small angle X… CONTINUE READING
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