Structural drivers of vulnerability to zoonotic disease in Africa

  title={Structural drivers of vulnerability to zoonotic disease in Africa},
  author={Vupenyu Dzingirai and Salome A. Bukachi and Melissa Leach and Lindiwe Mangwanya and Ian Scoones and Annie Wilkinson},
  journal={Philosophical Transactions of the Royal Society B: Biological Sciences},
This paper argues that addressing the underlying structural drivers of disease vulnerability is essential for a ‘One Health’ approach to tackling zoonotic diseases in Africa. Through three case studies—trypanosomiasis in Zimbabwe, Ebola and Lassa fever in Sierra Leone and Rift Valley fever in Kenya—we show how political interests, commercial investments and conflict and securitization all generate patterns of vulnerability, reshaping the political ecology of disease landscapes, influencing… 

Viral Zoonoses of National Importance in Ghana: Advancements and Opportunities for Enhancing Capacities for Early Detection and Response

A review of viral zoonoses of national importance and priority in Ghana, recent advancements in One Health capacities are highlighted, and opportunities for implementing One Health approaches to mitigate zoonotic disease threats are discussed.

EIDs and the Intersectional Health/Livelihoods Paradox in the Rural Global South

This article presents the framework of the intersectional health/livelihoods paradox to analyse how political economic processes incur land use change to create vulnerability to infectious disease,

People, Patches, and Parasites: The Case of Trypanosomiasis in Zimbabwe

An interdisciplinary study to investigate the spatial dynamics of human and animal trypanosomiasis in the Zambezi valley, Zimbabwe used a habitat niche model to identify changes in suitable habitat for tsetse fly vectors over time, and this is related to local villagers’ understandings of where flies are found.

Positioning zoonotic disease research in forced migration: A systematic literature review of theoretical frameworks and approaches

Addressing the emergence and spread of zoonoses in forced migration contexts requires more careful consideration and use of interdisciplinary research to integrate the contributions of social and natural science approaches.

Working together for prevention and control of zoonoses in India

Despite calls for collaborations across animal and human health sectors to control zoonoses, a ‘black-box’ approach to collaborations means there is limited understanding of their drivers,

A descriptive study of zoonotic disease risk at the human-wildlife interface in a biodiversity hot spot in South Western Uganda

Results revealed that hunting and bushmeat consumption is persistent for other perceived reasons like; bushmeat strengthens the body, helps mothers recover faster after delivery, boosts one's immunity and hunting is exercise for the body.

Vector-borne disease and climate change adaptation in African dryland social-ecological systems

A significant opportunity exists to simultaneously address the increasing threat of vector-borne diseases and climate change through methods aimed at strengthening adaptive capacity through community-based, participatory methods that build on local knowledge and are tailored to local ecological conditions, hold the best promise of reversing current trends.

Does urbanization make emergence of zoonosis more likely? Evidence, myths and gaps

A rapid evidence scan points to rapid demographic growth, migration and density, increased movement of people and animals, and changes in land uses as the main processes linked to the prevalence of zoonosis in the urban global South.

Geographical drivers and climate-linked dynamics of Lassa fever in Nigeria

It is shown that Lassa fever occurrence and incidence is influenced by climate, poverty, agriculture and urbanisation factors, and heterogeneous reporting processes and diagnostic laboratory access also appear to be important drivers of the patchy distribution of observed disease incidence.

Social and Political Dimensions of Disseminating Research Findings on Emerging Zoonotic Viruses: Our Experience in Sierra Leone

The complexities and challenges in disseminating research findings on the discovery of a new ebolavirus in bats in Sierra Leone are discussed, particularly in light of the previous outbreaks.



Local disease–ecosystem–livelihood dynamics: reflections from comparative case studies in Africa

  • M. LeachB. Bett J. Koninga
  • Environmental Science
    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2017
Understanding synergies, but also tensions and trade-offs, between ecosystem changes that benefit livelihoods and affect disease can inform ‘One Health’ approaches towards managing ecosystems in ways that reduce disease risks and burdens.

Zoonotic diseases: who gets sick, and why? Explorations from Africa

Abstract Global risks of zoonotic disease are high on policy agendas. Increasingly, Africa is seen as a ‘hotspot’, with likely disease spillovers from animals to humans. This paper explores the


TEN MONTHS AFTER THE FIRST INFECTION, Margaret Chan, Director-General of the World Health Organization, described the Ebola epidemic in West Africa as the ‘most severe acute public health emergency

Infections and inequalities : the modern plagues

Challenging the accepted methodologies of epidemiology and international health, Farmer points out that most current explanatory strategies, from 'cost-effectiveness' to patient 'noncompliance,' inevitably lead to blaming the victims.

Emerging Disease or Emerging Diagnosis?: Lassa Fever and Ebola in Sierra Leone

The piece will add to post-Ebola debates around preparedness by connecting intricate sociotechnical perspectives on disease emergence with the politics of science and global health and questioning the way priorities, risks, and problems have been conceptualized within this.

Global aspirations, local realities: the role of social science research in controlling neglected tropical diseases

  • K. Bardosh
  • Political Science
    Infectious Diseases of Poverty
  • 2014
This paper explores the social science/NTD literature and unpacks some of the ways in which social inquiry can help support effective and sustainable interventions, including on policy processes, health systems capacity, compliance and resistance to interventions, education and behaviour change, and community participation.

An assessment of the regional and national socio-economic impacts of the 2007 Rift Valley fever outbreak in Kenya.

The study highlights the need for greater sensitivity and analyses that address the multitude of economic losses resulting from an animal disease to better inform policy and decision making during animal health emergencies.

Outbreak of Ebola Virus Disease in Guinea: Where Ecology Meets Economy

The epicenter and site of first introduction is the region of Gueckedou in Guinea's remote southeastern forest region, spilling over into various other regions of Guinea as well as to neighboring Liberia and Sierra Leone.

Urbanisation, the Peri-urban Growth and Zoonotic Disease

Development must acknowledge these ever-burgeoning settlements and address the ability of the poor to live safely and include the provision of decent hygiene and sanitation, context-appropriate forms of disease containment, the recognition of the peri-urban poor as legitimate citizens, and improved understandings of human/animal interactions.

Epidemiological assessment of the Rift Valley fever outbreak in Kenya and Tanzania in 2006 and 2007.

Given the time required to mobilize large vaccine stocks, emergency vaccination did not contribute to the mitigation of explosive outbreaks of RVF and a phased approach balancing actions against increasing risk of an outbreak would be more effective.