Structural divergence between the human and chimpanzee genomes

  title={Structural divergence between the human and chimpanzee genomes},
  author={H. Kehrer-Sawatzki and D. Cooper},
  journal={Human Genetics},
  • H. Kehrer-Sawatzki, D. Cooper
  • Published 2006
  • Biology, Medicine
  • Human Genetics
  • The structural microheterogeneity evident between the human and chimpanzee genomes is quite considerable and includes inversions and duplications as well as deletions, ranging in size from a few base-pairs up to several megabases (Mb). Insertions and deletions have together given rise to at least 150 Mb of genomic DNA sequence that is either present or absent in humans as compared to chimpanzees. Such regions often contain paralogous sequences and members of multigene families thereby ensuring… CONTINUE READING
    59 Citations

    Figures, Tables, and Topics from this paper.

    Molecular mechanisms of chromosomal rearrangement during primate evolution
    • 73
    Comparative analysis of copy number variation in primate genomes
    • 6
    The origins and impact of primate segmental duplications.
    • 116
    • PDF
    Abundance of ultramicro inversions within local alignments between human and chimpanzee genomes
    • 13
    Adaptive evolution of UGT2B17 copy-number variation.
    • 117


    A genome-wide survey of structural variation between human and chimpanzee.
    • 184
    • Highly Influential
    • PDF
    Discovery of Human Inversion Polymorphisms by Comparative Analysis of Human and Chimpanzee DNA Sequence Assemblies
    • 170
    • Highly Influential
    • PDF
    Duplication and divergence in humans and chimpanzees
    • S. Wooding, L. Jorde
    • Biology, Medicine
    • BioEssays : news and reviews in molecular, cellular and developmental biology
    • 2006
    • 14
    • PDF
    A genome-wide comparison of recent chimpanzee and human segmental duplications
    • 376
    • Highly Influential
    • PDF
    DNA sequence and comparative analysis of chimpanzee chromosome 22
    • 223
    • PDF
    Recently mobilized transposons in the human and chimpanzee genomes.
    • 148
    • Highly Influential
    • PDF
    Duplication and positive selection among hominin-specific PRAME genes
    • 69
    Polymorphic micro-inversions contribute to the genomic variability of humans and chimpanzees
    • 23