Structural discrimination in the sparking function of sterols in the yeast Saccharomyces cerevisiae.

@article{Lorenz1989StructuralDI,
  title={Structural discrimination in the sparking function of sterols in the yeast Saccharomyces cerevisiae.},
  author={R. Lorenz and W. Casey and L. Parks},
  journal={Journal of bacteriology},
  year={1989},
  volume={171 11},
  pages={
          6169-73
        }
}
  • R. Lorenz, W. Casey, L. Parks
  • Published 1989
  • Biology, Medicine
  • Journal of bacteriology
  • A Saccharomyces cerevisiae sterol auxotroph, SPK14 (a hem1 erg6 erg7 ura), was constructed to test the ability of selected C-5,6 unsaturated sterols at growth-limiting concentrations to spark growth on bulk cholestanol. The native sterol, ergosterol, initiated growth faster and allowed a greater cell yield than did other sterols selectively altered in one or more features of the sterol. Although the C-5,6 unsaturation is required for the sparking function, the presence of the C-22 unsaturation… CONTINUE READING
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