Structural differences in the subfragment 1 and rod portions of myosin isozymes from adult and developing rat skeletal muscles.

@article{Bugaisky1984StructuralDI,
  title={Structural differences in the subfragment 1 and rod portions of myosin isozymes from adult and developing rat skeletal muscles.},
  author={Lawrence B. Bugaisky and Gillian Butler-Browne and Susan M. Sell and R. G. Whalen},
  journal={The Journal of biological chemistry},
  year={1984},
  volume={259 11},
  pages={7212-8}
}
During development of fast contracting skeletal muscle in the rat hindleg, embryonic and neonatal forms of the myosin heavy chain are present prior to the accumulation of the adult fast type ( Whalen , R. G., Sell, S. M., Butler-Browne, G.S., Schwartz, K., Bouveret, P., and Pinset -H arstr öm, I. (1981) Nature (Lond.) 292, 805-809). Polypeptide mapping of the heavy chain subunit using partial proteolysis in the presence of sodium dodecyl sulfate has shown differences in the cleavage patterns… CONTINUE READING