Structural determination of the vasoactive intestinal peptide by two‐dimensional 1H‐nmr spectroscopy

@article{Theriault1991StructuralDO,
  title={Structural determination of the vasoactive intestinal peptide by two‐dimensional 1H‐nmr spectroscopy},
  author={Y. Theriault and Y. Boulancer and S. St.-Pierre},
  journal={Biopolymers},
  year={1991},
  volume={31}
}
  • Y. Theriault, Y. Boulancer, S. St.-Pierre
  • Published 1991
  • Chemistry, Medicine
  • Biopolymers
  • The structure of the vasoactive intestinal peptide 1–28 in 40% 2,2,2‐trifluoroethanol was investigated by two‐dimensional 1H‐nmr spectroscopy. All 1H resonances, except the γ, δ, and ε protons of the lysine residues, could be sequentially assigned. Numerous intraresidual as well as short‐range interresidual nuclear Overhauser effect spectroscopy connectivities were observed. Using a variable‐target function minimization, a molecular model consisting of two helical stretches involving residues 7… CONTINUE READING
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