Structural determinants outside the PXDLS sequence affect the interaction of adenovirus E1A, C-terminal interacting protein and Drosophila repressors with C-terminal binding protein.

@article{Molloy2001StructuralDO,
  title={Structural determinants outside the PXDLS sequence affect the interaction of adenovirus E1A, C-terminal interacting protein and Drosophila repressors with C-terminal binding protein.},
  author={David P Molloy and Paola M Barral and K Helen Bremner and Phillip H. Gallimore and Roger J. A. Grand},
  journal={Biochimica et biophysica acta},
  year={2001},
  volume={1546 1},
  pages={55-70}
}
C-Terminal binding protein (CtBP) interacts with a highly conserved amino acid motif (PXDLS) at the C terminus of adenovirus early region 1A (AdE1A) protein. This amino acid sequence has recently been demonstrated in the mammalian protein C-terminal interacting protein (CtIP) and a number of Drosophila repressors including Snail, Knirps and Hairy. In the… CONTINUE READING