Structural considerations on the iridoids as anti-inflammatory agents.

  title={Structural considerations on the iridoids as anti-inflammatory agents.},
  author={Mar{\'i}a del Carmen Recio and Rosa Mar{\'i}a Giner and Salvador M{\'a}{\~n}ez and Jos{\'e} Luis R{\'i}os},
  journal={Planta medica},
  volume={60 3},
Twelve iridoid glycosides have been evaluated for their anti-inflammatory activity on two models: the carrageenan-induced mouse paw edema and the TPA-induced mouse ear edema. Loganic acid was the most active (44.4% edema inhibition) on the former test, whereas the catalpol derivative mixture isolated from Scrophularia, aucubin, verbenalin, and loganin, showed the highest activity (from 72.0 to 80.0% edema inhibition) on the latter. The results allowed us to establish the relationship between… 
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