Structural comparisons of TL antigens derived from normal and leukemia cells of Tl+ and TL- strains and relationship to genetically linked H-2 major histocompatibility complex products.

@article{Yokoyama1981StructuralCO,
  title={Structural comparisons of TL antigens derived from normal and leukemia cells of Tl+ and TL- strains and relationship to genetically linked H-2 major histocompatibility complex products.},
  author={Kazushige Yokoyama and Elisabeth Stockert and L. John Old and Stanley G. Nathenson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1981},
  volume={78 11},
  pages={7078-82}
}
Comparative tryptic peptide analysis was used to probe the structure of the TL products coded for by normally expressed TL alleles (Tlaa and Tlac haplotypes) and the structure of the TL product on ERLD, a TL+ leukemia occurring in a strain that does not normally express TL antigens (Tlab haplotype). In mice that have the Tlaa haplotype, the peptide maps of TL glycoproteins from normal thymocytes and from TL+ leukemias were identical, a finding that is consistent with the indistinguishable… CONTINUE READING

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