• DOI:10.1021/np070323+
• Corpus ID: 12792623

Structural characterization and DPPH radical scavenging activity of an arabinoglucogalactan from Panax notoginseng root.

@article{Wu2008StructuralCA,
  title={Structural characterization and DPPH radical scavenging activity of an arabinoglucogalactan from Panax notoginseng root.},
  author={Yalin Wu and Denong Wang},
  journal={Journal of natural products},
  year={2008},
  volume={71 2},
  pages={
          241-5
        }
}

• Yalin Wu, Denong Wang
• Published 11 January 2008
• Chemistry, Biology
• Journal of natural products

The structure of an antiradical arabinoglucogalactan ( 1) from Panax notoginseng roots was determined. This polymeric carbohydrate was obtained through successive phosphate buffer (pH 7.0) extraction after cold-water pretreatment and purification by ion-exchange and gel-filtration chromatography. Monosaccharide analysis, permethylation analysis, NaIO 4 and CrO 3 oxidations, Smith degradation, graded acid hydrolysis, and IR and NMR experiments indicated that 1 possesses a backbone of (1-->3)-linked beta- d-galactofuranosyl residues, with branches of alpha- l-Ara f-(1-->4)-beta- d-Glc p-(1--> residues at O-6. Additionally, 1 exhibited high scavenging activity against DPPH free radicals with a 50% scavenging concentration (SC50) of 11.72 +/- 0.91 microg/mL, suggesting that this arabinoglucogalactan is a potential antiradical.