Structural characteristics of the stable RNA introns of archaeal hyperthermophiles and their splicing junctions.

@article{LykkeAndersen1994StructuralCO,
  title={Structural characteristics of the stable RNA introns of archaeal hyperthermophiles and their splicing junctions.},
  author={Jens Lykke-Andersen and Roger A. Garrett},
  journal={Journal of molecular biology},
  year={1994},
  volume={243 5},
  pages={
          846-55
        }
}
Five pre-23 S rRNA introns have been characterized for hyperthermophilic archaea. The small ones constitute stable core structures while the three larger ones contain, in addition, open reading frames, two of which encode homing-type endonucleases. The higher order structures of in vitro transcripts of the introns and their exon-intron junctions were examined using chemical and ribonuclease probes specific for unpaired nucleotides, double helical regions and helix-loop junctions. The… CONTINUE READING

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