Structural changes of the homologues as a possible cause of abnormal disjunction in female mice heterozygous for Robertsonian translocations

Abstract

Mutations T, Fu and P-haplotype on chromosome 17 cause preferential transmission of the acrocentric homologues in the progeny of female mice heterozygotes for Robertsonian transloca-tions (Rb). The present results demonstrate that the influence of these mutations upon segregation is restricted to the Robertsonian translocations involving chromosome 17… (More)
DOI: 10.1186/1297-9686-20-3-299