Structural changes in the gut microbiome of constipated patients.

@article{Zhu2014StructuralCI,
  title={Structural changes in the gut microbiome of constipated patients.},
  author={L. Zhu and Wensheng Liu and Razan H Alkhouri and R. Baker and J. Bard and E. Quigley and S. Baker},
  journal={Physiological genomics},
  year={2014},
  volume={46 18},
  pages={
          679-86
        }
}
Previous studies using culture-based methods suggested an association between constipation and altered abundance of certain taxa of the colonic microbiome. [...] Key Method A cross-sectional pilot study using 16S rRNA gene pyrosequencing was performed to compare stool microbial composition of eight constipated patients and 14 nonconstipated controls. Only obese children were enrolled so that the microbiome features associated with constipation would not be obscured by those associated with obesity.Expand
133 Citations

Paper Mentions

Interventional Clinical Trial
Recent data support the use of specific probiotic strains in a pediatric population. However, given the wide number of commercial products available, and contradictory data in the… Expand
ConditionsConstipation, Digestive Signs and Symptoms, Infrequent or Difficult Evacuation, (+1 more)
InterventionDietary Supplement, Other
Beneficial effects of lactitol on the composition of gut microbiota in constipated patients.
  • 1
Gut Microbiota Composition Changes in Constipated Women of Reproductive Age
Alteration of Gut Microbiota and Efficacy of Probiotics in Functional Constipation
  • 38
  • PDF
Analysis of fecal microbiota in patients with functional constipation undergoing treatment with synbiotics
  • L. Huang, C. Kong, +7 authors H. Qin
  • Medicine
  • European Journal of Clinical Microbiology & Infectious Diseases
  • 2017
  • 10
Fecal Microbiota and Diet of Children with Chronic Constipation
  • 9
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 53 REFERENCES
Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa
  • 3,346
  • PDF
Microbiota and SCFA in Lean and Overweight Healthy Subjects
  • 1,557
Defining the healthy "core microbiome" of oral microbial communities
  • 773
  • PDF
Effect of Probiotics on Constipation, Fecal Azoreductase Activity and Fecal Mucin Content in the Elderly
  • 184
The intestinal ecosystem in chronic functional constipation
  • 115
  • PDF
Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes
  • 3,868
  • PDF
Methanobrevibacter smithii Is the Predominant Methanogen in Patients with Constipation-Predominant IBS and Methane on Breath
  • 91
  • PDF
The Effects of Circumcision on the Penis Microbiome
  • 182
  • Highly Influential
  • PDF
Alterations in the colonic flora and intestinal permeability and evidence of immune activation in chronic constipation.
  • 183
  • PDF
...
1
2
3
4
5
...