Structural changes in hippocampal subfields in major depressive disorder: a high-field magnetic resonance imaging study.

@article{Huang2013StructuralCI,
  title={Structural changes in hippocampal subfields in major depressive disorder: a high-field magnetic resonance imaging study.},
  author={Yushan Huang and Nick Coupland and R. Marc Lebel and Rawle Carter and Peter Seres and Alan H. Wilman and Nikolai V Malykhin},
  journal={Biological psychiatry},
  year={2013},
  volume={74 1},
  pages={62-8}
}
BACKGROUND Magnetic resonance imaging (MRI) has shown lower hippocampal volume in major depressive disorder (MDD). Preclinical and postmortem studies show that chronic stress and MDD may affect hippocampal subfields differently, but MRI spatial resolution has previously been insufficient to measure subfield volumes. METHODS Twenty MDD participants (9 unmedicated and 11 medicated, both > 6 months) and 27 healthy control subjects were studied. We used T2-weighted two-dimensional fast spin echo… CONTINUE READING
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