Structural changes in cytochrome c upon hydrogen-deuterium exchange.

@article{Hildebrandt1993StructuralCI,
  title={Structural changes in cytochrome c upon hydrogen-deuterium exchange.},
  author={Peter Hildebrandt and Françoise Vanhecke and G E Heibel and A. Grant Mauk},
  journal={Biochemistry},
  year={1993},
  volume={32 51},
  pages={14158-64}
}
The resonance Raman spectra of yeast ferri- and ferro-iso-1-cytochrome c dissolved in H2O and D2O are reported. Hydrogen exchange in the protein leads to distinct spectral changes of heme vibrational bands, particularly in the region between 670 and 710 cm-1 and at approximately 443 and approximately 450 cm-1. The latter two bands, which have previously… CONTINUE READING