Structural cerebral variations as useful endophenotypes in schizophrenia: do they help construct "extended endophenotypes"?

@article{Prasad2007StructuralCV,
  title={Structural cerebral variations as useful endophenotypes in schizophrenia: do they help construct "extended endophenotypes"?},
  author={Konasale M. Prasad and Matcheri S. Keshavan},
  journal={Schizophrenia bulletin},
  year={2007},
  volume={34 4},
  pages={
          774-90
        }
}
Endophenotypes represent intermediate phenotypes on the putative causal pathway from the genotype to the phenotype. They offer a potentially valuable strategy to examine the molecular etiopathology of complex behavioral phenotypes such as schizophrenia. Neurocognitive and neurophysiological impairments that suggest functional impairments associated with schizophrenia have been proposed as endophenotypes. However, few studies have examined the structural variations in the brain that might… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 54 CITATIONS, ESTIMATED 64% COVERAGE

Premorbid Cognitive Deficits in Young Relatives of Schizophrenia Patients

VIEW 4 EXCERPTS
CITES BACKGROUND

Tracing the development of psychosis and its prevention: What can be learned from animal models

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Convergent Approaches for Defining Functional Imaging Endophenotypes in Schizophrenia

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder

VIEW 1 EXCERPT

Electrophysiological Endophenotypes for Schizophrenia.

VIEW 1 EXCERPT
CITES BACKGROUND

FILTER CITATIONS BY YEAR

2009
2019

CITATION STATISTICS

  • 2 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 178 REFERENCES

Cortex mapping reveals regionally specific patterns of genetic and disease-specific gray-matter deficits in twins discordant for schizophrenia.

VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Anterior cingulate grey-matter deficits and cannabis use in first-episode schizophrenia.

VIEW 1 EXCERPT