• DOI:10.1038/s41586-020-2424-4
Corpus ID: 220295181

Structural cells are key regulators of organ-specific immune response

@article{Krausgruber2020StructuralCA,
  title={Structural cells are key regulators of organ-specific immune response},
  author={Thomas Krausgruber and N. Fortelny and Victoria Fife-Gernedl and Martin Senekowitsch and L. Schuster and A. Lercher and Amelie Nemc and C. Schmidl and Andr{\'e} F. Rendeiro and A. Bergthaler and C. Bock},
  journal={Nature},
  year={2020},
  volume={583},
  pages={296 - 302}
}

• Thomas Krausgruber, N. Fortelny, +8 authors C. Bock
• Published 2020
• Biology, Computer Science, Medicine
• Nature

The mammalian immune system implements a remarkably effective set of mechanisms for fighting pathogens 1 . Its main components are haematopoietic immune cells, including myeloid cells that control innate immunity, and lymphoid cells that constitute adaptive immunity 2 . However, immune functions are not unique to haematopoietic cells, and many other cell types display basic mechanisms of pathogen defence 3 – 5 . To advance our understanding of immunology outside the haematopoietic system, here… Expand

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