Structural cells are key regulators of organ-specific immune responses
@article{Krausgruber2020StructuralCA, title={Structural cells are key regulators of organ-specific immune responses}, author={Thomas Krausgruber and N. Fortelny and Victoria Fife-Gernedl and Martin Senekowitsch and L. Schuster and A. Lercher and Amelie Nemc and C. Schmidl and Andr{\'e} F. Rendeiro and Andreas Bergthaler and C. Bock}, journal={Nature}, year={2020}, volume={583}, pages={296-302} }
The mammalian immune system implements a remarkably effective set of mechanisms for fighting pathogens 1 . Its main components are haematopoietic immune cells, including myeloid cells that control innate immunity, and lymphoid cells that constitute adaptive immunity 2 . However, immune functions are not unique to haematopoietic cells, and many other cell types display basic mechanisms of pathogen defence 3 – 5 . To advance our understanding of immunology outside the haematopoietic system, here… CONTINUE READING
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