Structural brain abnormalities in women with subclinical depression, as revealed by voxel-based morphometry and diffusion tensor imaging.

@article{Hayakawa2013StructuralBA,
  title={Structural brain abnormalities in women with subclinical depression, as revealed by voxel-based morphometry and diffusion tensor imaging.},
  author={Yayoi K. Hayakawa and Hiroki Sasaki and Hidemasa Takao and Harushi Mori and Naoto Hayashi and Akira Kunimatsu and Shigeki Aoki and Kuni Ohtomo},
  journal={Journal of affective disorders},
  year={2013},
  volume={144 3},
  pages={263-8}
}
BACKGROUND Brain structural changes accompany major depressive disorder, but whether subclinical depression is accompanied by similar changes in brain volume and white matter integrity is unknown. By using voxel-based morphometry (VBM) of the gray matter and tract-specific analysis based on diffusion tensor imaging (DTI) of the white matter, we explored the extent to which abnormalities could be identified in specific brain structures of healthy adults with subclinical depression. METHODS The… CONTINUE READING