Structural biology of cadherins in the nervous system.

  title={Structural biology of cadherins in the nervous system.},
  author={Lawrence Shapiro and David R. Colman},
  journal={Current opinion in neurobiology},
  volume={8 5},
The complex functions of the nervous system reflect the coordinated action of intricately connected networks of neurons. Recent work has combined to suggest the importance of the cadherin family of cell adhesion molecules in specifying these connections at neural synapses. High-resolution structural studies and site-directed mutagenesis have revealed some… CONTINUE READING