Structural biology: Images from the surface of HIV

@article{Burton2006StructuralBI,
  title={Structural biology: Images from the surface of HIV},
  author={Dennis R. Burton},
  journal={Nature},
  year={2006},
  volume={441},
  pages={817-818}
}
ture is limited, and it is not clear how many spikes there are on each virus or how they are distributed. The structure of the extracellular part of gp41 has been resolved, but only in a conformation adopted after the virus connects with the target cell — little is known about what gp41 looks like before this interaction. The structures of isolated truncated gp120 ‘core’ molecules from HIV and SIV have also been solved and have been used to propose models for spikes in which gp120 and gp41… CONTINUE READING
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