Structural basis of influenza virus neutralization.

  title={Structural basis of influenza virus neutralization.},
  author={Thomas Han and Wayne A. Marasco},
  journal={Annals of the New York Academy of Sciences},
Although seasonal influenza vaccines play a valuable role in reducing the spread of virus at the population level, ongoing viral evolution to evade immune responses remains problematic. No current vaccines elicit enduring protection in the face of emerging and re-emerging influenza viruses that are rapidly undergoing antigenic drift. Eliciting broadly cross-neutralizing antibody (nAb) responses against influenza virus is a crucial goal for seasonal and pandemic influenza vaccine preparation… CONTINUE READING