Structural basis of a protein partner switch that regulates the general stress response of α-proteobacteria.

Abstract

α-Proteobacteria uniquely integrate features of two-component signal transduction (TCS) and alternative sigma factor (σ) regulation to control transcription in response to general stress. The core of this regulatory system is the PhyR protein, which contains a σ-like (SL) domain and a TCS receiver domain. Aspartyl phosphorylation of the PhyR receiver in… (More)
DOI: 10.1073/pnas.1116887109

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Cite this paper

@article{Herrou2012StructuralBO, title={Structural basis of a protein partner switch that regulates the general stress response of α-proteobacteria.}, author={Julien Herrou and Grant M Rotskoff and Yun Luo and Beno{\^i}t Roux and Sean Crosson}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2012}, volume={109 21}, pages={E1415-23} }