Structural basis for messenger RNA movement on the ribosome

@article{Yusupova2006StructuralBF,
  title={Structural basis for messenger RNA movement on the ribosome},
  author={Gulnara Yusupova and Lasse B. Jenner and Bernard Rees and Dino Moras and Marat Yusupov},
  journal={Nature},
  year={2006},
  volume={444},
  pages={391-394}
}
Translation initiation is a major determinant of the overall expression level of a gene. The translation of functionally active protein requires the messenger RNA to be positioned on the ribosome such that the start/initiation codon will be read first and in the correct frame. Little is known about the molecular basis for the interaction of mRNA with the ribosome at different states of translation. Recent crystal structures of the ribosomal subunits, the empty 70S ribosome and the 70S ribosome… 

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