Structural basis for exon recognition by a group II intron

  title={Structural basis for exon recognition by a group II intron},
  author={Navtej Toor and Kanagalaghatta R. Rajashankar and Kevin S. Keating and Anna M Pyle},
  journal={Nature Structural &Molecular Biology},
Free group II introns are infectious retroelements that can bind and insert themselves into RNA and DNA molecules via reverse splicing. Here we report the 3.4-Å crystal structure of a complex between an oligonucleotide target substrate and a group IIC intron, as well as the refined free intron structure. The structure of the complex reveals the conformation of motifs involved in exon recognition by group II introns. 

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