Structural and viscoelastic properties of actin/filamin networks: cross-linked versus bundled networks.

Abstract

The high diversity of cytoskeletal actin structures is accomplished by myriads of actin binding proteins (ABPs). Depending on its concentration, even a single type of ABP can induce different actin microstructures. Thus, for an overall understanding of the cytoskeleton, a detailed characterization of the cross-linker's effect on structural and mechanical properties of actin networks is required for each ABP. Using confocal microscopy and macrorheology, we investigate both cross-linked and bundled actin/filamin networks and compare their microstructures as well as their viscoelastic properties in the linear and the nonlinear regime.

DOI: 10.1016/j.bpj.2009.04.040

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@article{Schmoller2009StructuralAV, title={Structural and viscoelastic properties of actin/filamin networks: cross-linked versus bundled networks.}, author={Kurt M. Schmoller and Oliver Lieleg and Andreas R. Bausch}, journal={Biophysical journal}, year={2009}, volume={97 1}, pages={83-9} }