Structural and ultrastructural study of the rabbit testes exposed to carbamate insecticide

@article{Almiov2012StructuralAU,
  title={Structural and ultrastructural study of the rabbit testes exposed to carbamate insecticide},
  author={Viera Alm{\'a}{\vs}iov{\'a} and Katar{\'i}na Holovsk{\'a} and Lucia Tarabov{\'a} and Viera Cig{\'a}nkov{\'a} and Agne{\vs}a Luka{\vc}{\'i}nov{\'a} and Franti{\vs}ek Ni{\vs}tiar},
  journal={Journal of Environmental Science and Health, Part A},
  year={2012},
  volume={47},
  pages={1319 - 1328}
}
The present study was conducted to investigate the impact of carbamate insecticide - bendiocarb on the testicular structure of adult rabbits. Bendiocarb was perorally administered daily for 10 and 30 days, at a dose 5 mg/kg of body weight. After the histological sampling the tissues were investigated and compared with control. After the bendiocarb administration the absolute and relative testicular weight decreased significantly (P < 0.001) in both time periods. The testicular parenchyma showed… 
Ultrastructural changes in the rabbit liver induced by carbamate insecticide bendiocarb
TLDR
The results presented in this study indicate that both short and long-term administration of bendiocarb affects the liver ultrastructure and rapid onset of regeneration of the damaged tissue through activation of hepatocytes and oval cells.
Morphometric alterations, steatosis, fibrosis and active caspase‐3 detection in carbamate bendiocarb treated rabbit liver
TLDR
The results suggest that bendiocarb treatment leads to increased cell death, liver perisinusoidal fibrosis, and steatosis, especially during the long‐term administration.
Characterization of the Toxicological Effects of Aminocarb on Rats: Hematological, Biochemical, and Histological Analyses
TLDR
Subchronic effects on Wistar rats were investigated using hematological, biochemical, and histological techniques and indicated adverse effects of aminocarb on hepatic and renal functions, as well as on immune responsiveness at sublethal tested doses.
Subacute Effects of the Thiodicarb Pesticide on Target Organs of Male Wistar Rats: Biochemical, Histological, and Flow Cytometry Studies
TLDR
Results indicate marked systemic organ toxicity in rats after subacute exposure to thiodicarb, a carbamate pesticide widely used on crops.
Immunohistochemical Characterization of Lymphocytic CD3/CD20 and Macrophage CD68 in the Germinal Epithelium of Pb and Se+Zn Treated Adult Sprague-Dawley Rats
TLDR
CD3, CD20 and CD68 are distributed within the epithelium and the interstitium of the Pb treated testis, the expression level is influenced by the extent of the damage posed by Pb toxicity and not by the proliferative tendencies of Se+Zn treatment, which did protect the germinal epithelia and the macrophage/lymphocyte cell lines.
Physiological, Developmental, and Biomarker Responses of Zebrafish Embryos to Sub-Lethal Exposure of Bendiocarb
TLDR
The results highlight that the selected nonlethal concentrations of bendiocarb inflicted adverse effects resulting in embryo deformities, reduced body- and notochord length, oxidative stress, and altered heart rate in the studied model system.

References

SHOWING 1-10 OF 66 REFERENCES
Evaluation of chronic exposure of the male rat reproductive system to the insecticide methomyl.
TLDR
It has been concluded that chronic exposure to methomyl insecticide has deleterious effects on rat testes, and application of such insecticide should be limited to a designed program with special care in handling to limit or minimize its hazards.
Histological and ultrastructural studies of rats exposed to carbaryl.
The aim of the study was to assess the general toxic effects of dermally applied carbaryl, based on histological and ultrastructural examinations of internal organs and to relate these effects to
Short-term effects of carbendazim on the gross and microscopic features of the testes of Japanese quails (Coturnix coturnix japonica)
  • T. Aire
  • Biology
    Anatomy and Embryology
  • 2005
TLDR
The observed histological changes in the testis, due to carbendazim, were capable of causing prolonged infertility in exposed birds.
Ultrastructural evaluation of the effect of endosulfan on mice kidney.
TLDR
It is thought that oxidative stress may play a role to the mediator in changing configuration of cell membrane and seem to account for the morphologic alteration of kidney.
Histopathology of the male reproductive system induced by the fungicide benomyl.
TLDR
In conclusion, studies that reveal long term testicular atrophy following chronic or subchronic exposure to a toxicant should be re-examined for histopathological lesions in the efferent ductules and head of the epididymis.
Deformation of the rat Sertoli cell by oral administration of carbendazim (methyl 2-benzimidazole carbamate).
TLDR
Findings suggest that Sertoli cell cytoplasm, following carbendazim-induced sloughing, moves toward the base of the cellular axis.
Protective effect of vitamin E against carbendazim-induced testicular toxicity–histopathological evidences and reduced residue levels in testis and serum
TLDR
Protection against MBC-induced toxicity was observed with co-administration of vitamin E with MBC, and various histopathological changes were observed in testis of rats treated with M BC whereas these changes were absent in vitamin-E + MBC-treated rat testis.
Testicular damage after exposure to carbendazim depends on the number of patent efferent ductules.
TLDR
Whether or not the testis is able to survive the long-term deleterious effects of MBC depends largely EFD patency, and the number of normal seminiferous tubules increased progressively as the post-treatment interval increased.
Alterations in the rabbit lymphoid tissue after bendiocarb administration
TLDR
Observations of the small intestine, mucosal lymphoid tissue, lamina propria mucosae and a lymph node after administration of bendiocarb showed that on days 10 and 20 there was a significant increase in relativeVolume of medulla at the expense of the relative volume of the cortex and a decrease in the number of lymphocytes, however, an increase in diameter of lymphocyte was recorded.
...
1
2
3
4
5
...