Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.

Abstract

High resolution crystal structures have been determined for six chicken-type lysozymes that were constructed to investigate putative intermediates in the evolution of the lysozymes of modern game birds (Malcolm, B. A., Wilson, K. P., Matthews, B. W., Kirsch, J. F., and Wilson, A. C. (1990) Nature 345, 86-89). The amino acid replacements include Thr-40… (More)

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Cite this paper

@article{Wilson1992StructuralAT, title={Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.}, author={Kevin Wilson and Bruce A Malcolm and Brent Matthews}, journal={The Journal of biological chemistry}, year={1992}, volume={267 15}, pages={10842-9} }