Structural and immunochemical characterization of the type VIII group B Streptococcus capsular polysaccharide.

@article{Kogan1996StructuralAI,
  title={Structural and immunochemical characterization of the type VIII group B Streptococcus capsular polysaccharide.},
  author={Grigorij Kogan and Du{\vs}an Uhr{\'i}n and J. R. Brisson and Lawrence C. Paoletti and April E Blodgett and Dennis L Kasper and Harold J. Jennings},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 15},
  pages={8786-90}
}
The type VIII capsular polysaccharide has been isolated and purified from a newly described strain of group B Streptococcus which is a leading cause of sepsis and neonatal meningitis in Japan. The polysaccharide contains D-glucose, D-galactose, L-rhamnose, and sialic acid in the molar ratio 1:1:1:1. By means of high resolution 1H nuclear magnetic resonance (1H NMR), 13C NMR, and homo- and heterocorrelated NMR, the repeating unit structure of the type VIII polysaccharide was delineated as the… CONTINUE READING

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