Structural and genetic analyses of HLA class I molecules using monoclonal xenoantibodies.

@article{Reba1983StructuralAG,
  title={Structural and genetic analyses of HLA class I molecules using monoclonal xenoantibodies.},
  author={N Reba{\"i} and Bernard Malissen},
  journal={Tissue antigens},
  year={1983},
  volume={22 2},
  pages={107-17}
}
The monoclonal antibodies B1.23.2 and B9.12 were developed to characterize human class I major histocompatibility gene products. They detect two different epitopes and define on a given lymphoblastoid B cell line two subsets of beta 2 microglobulin-complexed HLA class I molecules. One subset reacts with B9.12 and B1.23.2 and the other one expresses only the B9.12 epitope. Binding assays were performed on C3H mouse L cells which had been transformed with various single HLA-class I genes and the… CONTINUE READING

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