Structural and functional properties of rat liver mitochondria in hexachlorobenzene induced experimental porphyria.

@article{Masini1984StructuralAF,
  title={Structural and functional properties of rat liver mitochondria in hexachlorobenzene induced experimental porphyria.},
  author={Alberto Masini and D Ceccarelli-Stanzani and Tommaso Trenti and Emilio Rocchi and Ezio Ventura},
  journal={Biochemical and biophysical research communications},
  year={1984},
  volume={118 1},
  pages={356-63}
}
A possible link between changes in iron and porphyrin content in liver mitochondria, from rats treated with either hexachlorobenzene, iron, or hexachlorobenzene plus iron, as a function of treatment time and their structural-functional properties, has been investigated. Normal oxidative phosphorylation in mitochondria from rats treated with iron has been shown. By contrast a significant and constant uncoupling of the phosphorylative process, fully reversed by albumin, in mitochondria from rats… CONTINUE READING

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