Structural and functional insights into nucleocytoplasmic transport.

@article{Beck2008StructuralAF,
  title={Structural and functional insights into nucleocytoplasmic transport.},
  author={Martin Beck and Ohad Medalia},
  journal={Histology and histopathology},
  year={2008},
  volume={23 8},
  pages={1025-33}
}
The cell nucleus is surrounded by a double membrane system, the nuclear envelope (NE), with the outer nuclear membrane being continuous with the endoplasmic reticulum. Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes, forming aqueous channels that allow free diffusion of small molecules but that also mediate the energy-dependent… CONTINUE READING