Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex.

Abstract

RuvBL1 (RuvB-like 1) and its homolog RuvBL2 are evolutionarily highly conserved AAA(+) ATPases essential for many cellular activities. They play an important role in chromatin remodeling, transcriptional regulation and DNA damage repair. RuvBL1 and RuvBL2 are overexpressed in different types of cancer and interact with major oncogenic factors, such as… (More)
DOI: 10.1016/j.jsb.2011.09.001

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Cite this paper

@article{Gorynia2011StructuralAF, title={Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex.}, author={Sabine Gorynia and Tiago M. Bandeiras and Filipa G Pinho and Colin E McVey and Clemens Vonrhein and Adam Round and Dmitri I. Svergun and Peter Donner and Pedro Moreno Mat{\'i}as and Maria Arm{\'e}nia Carrondo}, journal={Journal of structural biology}, year={2011}, volume={176 3}, pages={279-91} }