Structural and functional heterogeneity of nuclear bodies.

  title={Structural and functional heterogeneity of nuclear bodies.},
  author={Donald B Bloch and Jean Daniel Chiche and Dorothea Orth and Suzanne de la Monte and Anthony Rosenzweig and Kenneth D. Bloch},
  journal={Molecular and cellular biology},
  volume={19 6},
The nuclear body is a cellular structure that appears to be involved in the pathogenesis of acute promyelocytic leukemia and viral infection. In addition, the nuclear body is a target of autoantibodies in patients with the autoimmune disease primary biliary cirrhosis. Although the precise function of the nuclear body in normal cellular biology is unknown, this structure may have a role in the regulation of gene transcription. In a previous investigation, we identified a leukocyte-specific… CONTINUE READING


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