Structural and functional correlates of behavioral pattern separation in the hippocampus and medial temporal lobe.

@article{Doxey2015StructuralAF,
  title={Structural and functional correlates of behavioral pattern separation in the hippocampus and medial temporal lobe.},
  author={Christopher R Doxey and C. Brock Kirwan},
  journal={Hippocampus},
  year={2015},
  volume={25 4},
  pages={524-33}
}
Structures of the medial temporal lobe (MTL) are known to be involved in declarative memory processes. However, little is known about how age-related changes in MTL structures, white matter integrity, and functional connectivity affect pattern separation processes in the MTL. In this study, we used magnetic resonance imaging (MRI) to measure the volumes of MTL regions of interest, including hippocampal subfields (dentate gyrus, CA3, CA1, and subiculum) in healthy older and younger adults… CONTINUE READING
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