Structural and functional characterization of the zebrafish gene for glial fibrillary acidic protein, GFAP.

@article{Nielsen2003StructuralAF,
  title={Structural and functional characterization of the zebrafish gene for glial fibrillary acidic protein, GFAP.},
  author={Anders Lade Nielsen and Arne Lund J\orgensen},
  journal={Gene},
  year={2003},
  volume={310},
  pages={123-32}
}
Glial fibrillary acidic protein, GFAP, is an astrocyte-specific member of the family of intermediate filament proteins which are involved in formation of the cytoskeletal structure. We here present a characterization of the zebrafish GFAP gene and corresponding protein. The zebrafish GFAP gene have the same exon-intron organization as the mammalian orthologoue genes. Comparison of the protein with mammalian GFAP shows that the amino acid sequence is highly conserved in the rod and tail domains… CONTINUE READING

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