Structural and functional characterization of CATH_BRALE, the defense molecule in the ancient salmonoid, Brachymystax lenok.

@article{Li2013StructuralAF,
  title={Structural and functional characterization of CATH_BRALE, the defense molecule in the ancient salmonoid, Brachymystax lenok.},
  author={Zheng Li and Songyan Zhang and Jiuxiang Gao and Huijuan Guang and Yuanyong Tian and Zongmao Zhao and Yunfei Wang and Haining Yu},
  journal={Fish & shellfish immunology},
  year={2013},
  volume={34 1},
  pages={
          1-7
        }
}
Thick-lipped lenok, Brachymystax lenok is one of the ancient fish species in China and northeast Asia countries. Due to the overfishing, the population of lenok has been declined significantly. Cathelicidins are innate immune effectors that possess both bactericidal activities and immunomodulatory functions. This report identifies and characterizes the salmonoid cathelicidin (CATH_BRALE) from this ancient fish. It consists of open reading frame (ORF) of 886 bp encoding the putative peptide of… CONTINUE READING

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RI Lehrer
  • Fish & Shellfish Immunology
  • 2013
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