Structural and functional characterization of diffusible signal factor family quorum-sensing signals produced by members of the Burkholderia cepacia complex.

@article{Deng2010StructuralAF,
  title={Structural and functional characterization of diffusible signal factor family quorum-sensing signals produced by members of the Burkholderia cepacia complex.},
  author={Yinyue Deng and Ji'en Wu and Leo Eberl and Lian-Hui Zhang},
  journal={Applied and environmental microbiology},
  year={2010},
  volume={76 14},
  pages={4675-83}
}
Previous work has shown that Burkholderia cenocepacia produces the diffusible signal factor (DSF) family signal cis-2-dodecenoic acid (C(12):Delta(2), also known as BDSF), which is involved in the regulation of virulence. In this study, we determined whether C(12):Delta(2) production is conserved in other members of the Burkholderia cepacia complex (Bcc) by using a combination of high-performance liquid chromatography, mass spectrometry, and bioassays. Our results show that five Bcc species are… CONTINUE READING

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