Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain.

Abstract

Ebolaviruses are causative agents of lethal hemorrhagic fever in humans and nonhuman primates. Among the filoviruses characterized thus far, Reston Ebola virus (REBOV) is the only Ebola virus that is nonpathogenic to humans despite the fact that REBOV can cause lethal disease in nonhuman primates. Previous studies also suggest that REBOV is less effective… (More)
DOI: 10.1016/j.jmb.2010.04.022

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