Structural and functional brain signatures of C9orf72 in motor neuron disease.

Abstract

This study investigated structural and functional magnetic resonance imaging abnormalities in hexanucleotide repeat expansion in chromosome 9 open reading frame 72 (C9orf72) motor neuron disease (MND) relative to disease severity-matched sporadic MND cases. We enrolled 19 C9orf72 and 67 disease severity-matched sporadic MND patients, and 22 controls… (More)
DOI: 10.1016/j.neurobiolaging.2017.05.024

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@article{Agosta2017StructuralAF, title={Structural and functional brain signatures of C9orf72 in motor neuron disease.}, author={Federica Agosta and Pilar M. Ferraro and Nilo Riva and Edoardo Gioele Spinelli and Teuta Domi and Paola Carrera and Massimiliano Copetti and Yuri Matteo Falzone and Maurizio Ferrari and Christian Lunetta and Giancarlo Comi and Andrea Falini and Angelo Quattrini and Massimo Filippi}, journal={Neurobiology of aging}, year={2017}, volume={57}, pages={206-219} }