Structural and functional brain development after hydrocortisone treatment for neonatal chronic lung disease.

@article{Lodygensky2005StructuralAF,
  title={Structural and functional brain development after hydrocortisone treatment for neonatal chronic lung disease.},
  author={Gregory A. Lodygensky and Karin J. Rademaker and Slava Zimine and Marianne Gex-Fabry and Arno F Lieftink and François Lazeyras and Floris Groenendaal and Linda S de Vries and Petra S. Huppi},
  journal={Pediatrics},
  year={2005},
  volume={116 1},
  pages={1-7}
}
OBJECTIVE There is much concern about potential neurodevelopmental impairment after neonatal corticosteroid treatment for chronic lung disease. Dexamethasone is the corticosteroid most often used in this clinical setting, and it has been shown to impair cortical growth among preterm infants. This study evaluated long-term effects of prematurity itself and of neonatal hydrocortisone treatment on structural and functional brain development using three-dimensional MRI with advanced image… CONTINUE READING